Peptides

Selector

Please Select a Classification Method for Browsing Cyclic Peptides

  Data Source

  Assay Type

  Monomer Length

  Molecule Shape

Peptides Classified by Data Source
Source Name Type Data Number
ALL 7,451
(1)  2006_Rezai_1 Article 10
(2)  2006_Rezai_2 Article 11
(3)  2011_White Article 10
(4)  2012_Rand Article 16
(5)  2013_CHUGAI Patent 878
(6)  2013_Zaretsky Article 2
(7)  2014_Nielsen Article 4
(8)  2015_Ahlbach Article 34
(9)  2015_Bockus_1 Article 16
(10) 2015_Bockus_2 Article 17
(11) 2015_Hewitt Article 18
(12) 2015_Lewis Article 2
(13) 2015_Marelli Article 10
(14) 2015_Nielsen Article 3
(15) 2015_Schwochert Article 13
(16) 2015_Wang Article 62
(17) 2016_Fouche Article 15
(18) 2016_Frost Article 12
(19) 2016_Furukawa Article 688
(20) 2016_Hickey Article 18
(21) 2016_Schwochert Article 8
(22) 2017_Boehm Article 14
(23) 2017_Price Article 2
(24) 2017_Pye Article 21
(25) 2018_Buckton Article 19
(26) 2018_CHUGAI Patent 374
(27) 2018_García-Pindado Article 4
(28) 2018_Kaneda Article 7
(29) 2018_Lee Article 6
(30) 2018_Naylor Article 81
(31) 2018_Ramalho Article 10
(32) 2019_Ono Article 8
(33) 2020_Barlow Article 26
(34) 2020_Furukawa Article 36
(35) 2020_Hosono Article 11
(36) 2020_Le Roux Article 47
(37) 2020_Townsend Article 3,086
(38) 2021_Comeau Article 42
(39) 2021_Golosov Article 27
(40) 2021_Kelly Article 1,519
(41) 2021_Lee Article 5
(42) 2021_Wang Article 24
(43) 2022_Bhardwaj Article 136
(44) 2022_Lee Article 24
(45) 2022_Saunders Article 11
(46) 2022_Taechalertpaisarn Article 52
(47) 2022_Tamura Article 12

  • CycPeptMPDB currently contains 7,334 structurally diverse cyclic peptides collected from 47 literature.
  • Some peptides overlapped in structure between different literature and had different membrane permeability measurements, they were recorded as separate data in CycPeptMPDB (there were 7,451 peptides including duplicated structures).

Peptides Classified by Assay Type
Assay Type Data Number
ALL 7,451
(1) PAMPA 6,941
(2) Caco2 649
(3) MDCK 40
(4) RRCK 186

  • All measured values were recorded when there were measurements by multiple assays in one literature. Therefore, the sum of the number of data in each subset when classified by Assay Type is greater than the total number.

Peptides Classified by Monomer Length
Monomer Length Data Number
ALL 7,451
(1)   2 4
(2)   3 49
(3)   4 55
(4)   5 80
(5)   6 2,148
(6)   7 2,058
(7)   8 111
(8)   9 111
(9)  10 1,730
(10) 11 550
(11) 12 234
(12) 13 170
(13) 14 125
(14) 15 26

Peptides Classified by Molecule Shape
Molecule Shape Data Number
ALL 7,451
(1) Circle 5,115
(2) Lariat 2,336

  • Circle: cyclization position is the N- and C-terminal of sequence.
  • Lariat: cyclization position is not at the terminal of the sequence (one or more monomers in the side chain).